Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 259
interventional 166
Observational 83
Registry 10

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Procedure 51
Other 23
Drug 20
Device 11
Drug|placebo 11
Drug|Procedure 9
Behavioral 5
Device|Procedure 5
Device|Other 4
Device|Drug|Procedure 3
Diagnostic Test 3
placebo|Procedure 3
Device|Drug 2
Dietary Supplement 2
Dietary Supplement|placebo 2
Drug|Other 2
Other|Procedure 2
Behavioral|Procedure 1
Biological 1
Biological|Drug 1
Biological|placebo 1
Device|placebo 1
Drug|placebo|Procedure 1
Genetic 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
NA 35
Brazil 29
United States 28
Turkey 9
Italy 8
Norway 6
India 5
Canada 4
Egypt 4
France 4
Germany 3
Pakistan 3
Sweden 3
Chile 2
Hong Kong 2
Korea, Republic of 2
Malaysia 2
Netherlands 2
United Kingdom 2
Australia 1
Greece 1
Hungary 1
Iraq 1
Japan 1
Nigeria 1
Norway|Turkey 1
Poland 1
Saudi Arabia 1
Slovenia 1
Spain 1
United Arab Emirates 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 153
2 9
3 1
4 1
6 1
26 1

Phase

Phase Study_Count
N/A 115
Phase 4 23
Phase 2 13
Phase 3 8
Phase 2/Phase 3 6
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 11
2 109
3 28
4 7
5 3
6 3
NA 5

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 18 2.0000 15 10.00000 10.00 15.00000
1st Qu. 18 30.0000 40 21.00000 32.25 30.50000
Median 18 51.0000 60 28.00000 61.00 41.00000
Mean 18 157.1739 122 26.66667 224.75 56.69565
3rd Qu. 18 87.0000 154 33.50000 176.50 61.00000
Max. 18 9365.0000 400 40.00000 1101.00 303.00000

Trial Group Type

group_type Group_Count
Experimental 158
Active Comparator 122
Placebo Comparator 47
No Intervention 25
Other 17
Sham Comparator 5
NA 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 136
Single Group Assignment 15
Crossover Assignment 11
Factorial Assignment 3
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 115
Prevention 23
Diagnostic 11
Supportive Care 7
Other 4
NA 3
Basic Science 2
Health Services Research 1

Observational Studies

Studies by Country

Country Study_Count
NA 19
United States 19
Turkey 8
India 6
Brazil 5
Italy 5
Egypt 3
France 3
Germany 2
Romania 2
Turkey|United Kingdom 2
Argentina 1
Canada 1
Denmark 1
Greece 1
Poland 1
Spain 1
Sweden 1
Syrian Arab Republic 1
United Kingdom 1

Sites per Study

Site_count Study_Count
1 77
2 3
5 2
6 1

Enrollment Metrics

Measure Observational
Min 15.0000
1st Qu 60.0000
Median 88.0000
Mean 835.9759
3rd Qu 200.0000
Max 45000.0000

Observation Model

observational_model Study_Count
Case-Control 24
Cohort 24
Case Control 14
Other 14
Case-Only 5
NA 2

Time Perspective

time_perspective Study_Count
Cross-Sectional 34
Prospective 34
Other 8
Retrospective 6
NA 1

Registries

Studies by Country

Country Study_Count
NA 5
Egypt 1
Italy 1
Japan 1
Spain 1
Turkey 1

Sites per Study

Site_count Study_Count
1 10

Enrollment Metrics

Measure Registries
Min 39.0
1st Qu 82.5
Median 109.5
Mean 181.8
3rd Qu 120.0
Max 750.0

Registry Model

observational_model Study_Count
Case-Control 6
Cohort 3
Other 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 4
Other 3
Prospective 3

Follow-up

target_duration Study_Count
1 Day 2
10 Months 1
12 Months 1
15 Days 1
2 Days 1
2 Weeks 1
2 Years 1
3 Days 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03368430 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT03368430 Completed Mansoura University 2017-06-08
NCT03364751 Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome https://ClinicalTrials.gov/show/NCT03364751 Completed Philip Morris Products S.A. 2018-12-21
NCT03336957 Stress and Gingival Inflammation in Non-pregnant and Pregnant Women https://ClinicalTrials.gov/show/NCT03336957 Completed Tokat Gaziosmanpasa University 2017-01-01
NCT03316755 Risk Perception of Periodontal Disease https://ClinicalTrials.gov/show/NCT03316755 Completed University of Benin 2017-10-04
NCT02514226 Evaluation of Periodontal Treatment in Patients With Bronchiectasis https://ClinicalTrials.gov/show/NCT02514226 Enrolling by invitation University of Nove de Julho 2020-07-31
NCT03262402 Effects of Periodontal Treatment on HIV-infected Patients https://ClinicalTrials.gov/show/NCT03262402 Completed University of Sao Paulo 2018-08-02
NCT03262077 Dose Parameters for Photodynamic Therapy on Periodontal Disease https://ClinicalTrials.gov/show/NCT03262077 Completed University of Nove de Julho 2017-06-26
NCT03241953 COMPARISION OF DIFFERENT TREATMENT METHODS OF PERI-IMPLANTITIS https://ClinicalTrials.gov/show/NCT03241953 Completed Necmettin Erbakan University 2016-11-20
NCT03227367 Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials. https://ClinicalTrials.gov/show/NCT03227367 Completed Meenakshi Ammal Dental College and Hospital 2016-04-13
NCT03219840 Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis https://ClinicalTrials.gov/show/NCT03219840 Completed The University of Texas Health Science Center, Houston 2018-09-08
NCT03198832 oxLDL in Diabetes Mellitus Patients and Disease Periodontal https://ClinicalTrials.gov/show/NCT03198832 Completed Universidade Estadual Paulista Júlio de Mesquita Filho 2016-08-26
NCT03197610 The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score https://ClinicalTrials.gov/show/NCT03197610 Completed Yuzuncu Yıl University 2016-07-01
NCT03196648 Randomized Trial of a Gum Health Formulation https://ClinicalTrials.gov/show/NCT03196648 Completed Glo Science, Inc. 2016-11-30
NCT03191721 Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment. https://ClinicalTrials.gov/show/NCT03191721 Completed University of Guarulhos 2014-12-31
NCT03190512 Periodontal Treatment and Psychology https://ClinicalTrials.gov/show/NCT03190512 Completed Tokat Gaziosmanpasa University 2016-03-31
NCT03181386 Tooth Extraction in Patients With Atrial Fibrillation in Use of New Oral Anticoagulants https://ClinicalTrials.gov/show/NCT03181386 Active, not recruiting University of Sao Paulo General Hospital 2020-07-30
NCT03117153 Effect of a Liquid Toothpaste on Periodontal Disease https://ClinicalTrials.gov/show/NCT03117153 Completed Dong-A Pharmaceutical 2014-09-15
NCT03102892 Antimicrobial Photodynamic Therapy on Periodontal Treatment and Salivary Status of Type 1 Diabetes Mellitus Patients https://ClinicalTrials.gov/show/NCT03102892 Recruiting University of Sao Paulo 2020-10-10
NCT03095976 Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration for Periodontal Intrabony Defects and Grade II Furcation Defects. https://ClinicalTrials.gov/show/NCT03095976 Recruiting Indiana University 2019-10-15
NCT02982681 Bioactive Glass and Platelet Rich Fibrin in Intrabony Defects https://ClinicalTrials.gov/show/NCT02982681 Completed Dr. D. Y. Patil Dental College & Hospital 2016-08-31
NCT02938988 Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down’s Syndrome Patients https://ClinicalTrials.gov/show/NCT02938988 Completed University of Sao Paulo 2016-10-31
NCT02935322 Interaction Between Chlorhexidine and Fluoride https://ClinicalTrials.gov/show/NCT02935322 Completed University of Oslo 2011-12-31
NCT02914743 Providing Preventive Periodontal Treatment to Hospitalized Patients With Diabetes https://ClinicalTrials.gov/show/NCT02914743 Completed Massachusetts General Hospital 2017-10-02
NCT02866929 A Biotype Enhancing Strategy For The Patient Undergoing Accelerated Orthodontics https://ClinicalTrials.gov/show/NCT02866929 Active, not recruiting CES University 2018-06-30
NCT02793453 Antimicrobial Peptides in Periodontitis https://ClinicalTrials.gov/show/NCT02793453 Completed CHU de Reims 2016-03-23
NCT02774967 Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions https://ClinicalTrials.gov/show/NCT02774967 Completed University of Sao Paulo 2016-01-31
NCT02761993 Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis https://ClinicalTrials.gov/show/NCT02761993 Completed Noveome Biotherapeutics, formerly Stemnion 2017-10-31
NCT02756377 A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases https://ClinicalTrials.gov/show/NCT02756377 Completed Islamic Azad University, Tehran 2015-04-30
NCT02735837 The Effect of Topical Doxycycline Gel on HbA1c in Patients With Type 2 Diabetes Mellitus(DM) ® https://ClinicalTrials.gov/show/NCT02735837 Completed Islamic Azad University, Tehran 2016-03-31
NCT02670135 Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers https://ClinicalTrials.gov/show/NCT02670135 Completed Colgate Palmolive 2016-07-31
NCT02666573 Photodynamic Therapy During Supportive Periodontal Therapy https://ClinicalTrials.gov/show/NCT02666573 Completed National University, Singapore 2014-12-31
NCT02618486 The Effects of Obesity on Non Surgical Periodontal Therapy https://ClinicalTrials.gov/show/NCT02618486 Completed University of Malaya 2015-09-30
NCT02613468 Periodontal Condition in Pregnancy and Low Birth Delivery Incidence https://ClinicalTrials.gov/show/NCT02613468 Completed Ondokuz Mayıs University 2004-12-31
NCT02585596 A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease. https://ClinicalTrials.gov/show/NCT02585596 Completed Yuhan Corporation 2016-12-28
NCT02560870 Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal Diseases https://ClinicalTrials.gov/show/NCT02560870 Completed Islamic Azad University, Tehran 2015-04-30
NCT02543502 Treatment of Periodontal Disease in Patients With Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT02543502 Completed Instituto de Cardiologia do Rio Grande do Sul 2015-01-31
NCT02541032 PeRiodontal Treatment to Eliminate Minority InEquality and Rural Disparities in Stroke https://ClinicalTrials.gov/show/NCT02541032 Recruiting University of South Carolina 2019-06-30
NCT02538237 the Effect of Sub-gingival Irrigation With Ibuprofen 2% Mouthwash in Treatment of Periodontal Diseases. https://ClinicalTrials.gov/show/NCT02538237 Completed Islamic Azad University, Tehran 2014-08-31
NCT02508415 Relationship Between Obesity and Periodontal Disease https://ClinicalTrials.gov/show/NCT02508415 Completed University of Malaya 2014-01-31
NCT02500654 Regenerative Surgical Treatment of Peri-implantitis https://ClinicalTrials.gov/show/NCT02500654 Completed Region Gävleborg 2014-01-31
NCT02487186 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. https://ClinicalTrials.gov/show/NCT02487186 Completed University of Campinas, Brazil 2014-12-31
NCT02474498 EMD and/or Bone Substitute for the Treatment of Class II Furcations https://ClinicalTrials.gov/show/NCT02474498 Completed University of Campinas, Brazil 2014-12-31
NCT02463006 Porous and Non-porous Bone Grafts in Intra-bony Periodontal Defects https://ClinicalTrials.gov/show/NCT02463006 Completed Dr. D. Y. Patil Dental College & Hospital 2014-09-30
NCT02461030 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment https://ClinicalTrials.gov/show/NCT02461030 Completed University of Campinas, Brazil 2014-11-30
NCT02460926 Acute Phase Response & Periodontal Treatment https://ClinicalTrials.gov/show/NCT02460926 Completed University of Pisa 2013-10-31
NCT03386877 Periodontal Regeneration Using Dental Pulp Stem Cells (DPSCs) https://ClinicalTrials.gov/show/NCT03386877 Completed University of Turin, Italy 2017-04-28
NCT02375178 Antimicrobial Activity of Two Mouthwashes https://ClinicalTrials.gov/show/NCT02375178 Completed Universidade do Vale do Sapucai 2014-10-31
NCT02368678 “Study of Halitosis in Patients With Advanced Chronic Periodontitis” https://ClinicalTrials.gov/show/NCT02368678 Completed Federal University of Minas Gerais 2014-05-31
NCT02333227 Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi https://ClinicalTrials.gov/show/NCT02333227 Active, not recruiting Baylor College of Medicine 2020-12-31
NCT02220751 Diagnostic Biomarkers Related to Periodontal Disease Activity in Diabetic https://ClinicalTrials.gov/show/NCT02220751 Completed University of Sao Paulo 2011-09-30
NCT02185209 Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics https://ClinicalTrials.gov/show/NCT02185209 Recruiting Karolinska Institutet 2021-10-31
NCT02180932 Towards a Viral Etiology of Periodontal Disease in Relation to Radiotherapy Treatment of Head and Neck Cancers https://ClinicalTrials.gov/show/NCT02180932 Completed Centre Hospitalier Universitaire de Nice 2015-07-31
NCT02172716 Disruption of Immune Homeostasis in Type 2 Diabetics With Generalized Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02172716 Completed University of Sao Paulo 2015-05-31
NCT02126267 Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection https://ClinicalTrials.gov/show/NCT02126267 Completed Centro Universitario de Lavras 2014-02-28
NCT02102360 Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. https://ClinicalTrials.gov/show/NCT02102360 Completed University of Sao Paulo 2013-11-30
NCT01291875 Periodontal Treatment and Metabolic Control in Type 2 Diabetic Patients https://ClinicalTrials.gov/show/NCT01291875 Completed University of Sao Paulo 2014-02-28
NCT01951547 The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians https://ClinicalTrials.gov/show/NCT01951547 Completed University of Malaya 2011-12-31
NCT01950962 Role Of Phospholipid Transfer Proteins (Pltp) On Endotoxemia Caused By Buccal Inflammation https://ClinicalTrials.gov/show/NCT01950962 Completed Centre Hospitalier Universitaire Dijon 2014-06-12
NCT04450849 Regenerative Potential of a Collagen Membrane Associated or Not to Bovine Bone in Class II Furcation Defects. https://ClinicalTrials.gov/show/NCT04450849 Completed University of Sao Paulo 2019-06-15
NCT01852253 Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment https://ClinicalTrials.gov/show/NCT01852253 Completed University Medical Center Groningen 2013-04-30
NCT01811615 Efficacy of New Alcohol Free Mouthrinses https://ClinicalTrials.gov/show/NCT01811615 Completed University of Witten/Herdecke 2011-02-28
NCT01802216 Kidney and Periodontal Disease Study https://ClinicalTrials.gov/show/NCT01802216 Completed University of California, San Francisco 2017-09-30
NCT01798225 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population https://ClinicalTrials.gov/show/NCT01798225 Completed Medical University of South Carolina 2010-01-31
NCT01742559 The Anesthetic Effect of Anterior Middle Superior Alveolar Technique https://ClinicalTrials.gov/show/NCT01742559 Completed State University of Maringá 2010-08-31
NCT01718912 Periodontal Disease Treatment of a Physically Challenged Population https://ClinicalTrials.gov/show/NCT01718912 Completed Oravital Inc 2014-09-30
NCT01670305 Photodynamic Therapy and Periodontal Therapy. A Clinical, Microbiological and Immunoenzymatic Analysis https://ClinicalTrials.gov/show/NCT01670305 Completed Paulista University 2011-05-31
NCT01639183 Power Toothbrush Use in Nursing Homes to Eliminate Mouth and Body Inflammation https://ClinicalTrials.gov/show/NCT01639183 Completed University of Manitoba 2013-07-31
NCT01595594 Comparison Between aPDT and Systemic Doxycycline on Non-surgical Periodontal Therapy in Type 2 Diabetics https://ClinicalTrials.gov/show/NCT01595594 Completed University of Sao Paulo 2012-04-30
NCT01591616 Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel https://ClinicalTrials.gov/show/NCT01591616 Completed Dentsply International 2012-04-30
NCT01533792 Effect of Non-surgical Periodontal Treatment https://ClinicalTrials.gov/show/NCT01533792 Completed Universidade Federal do Maranhão 2010-12-31
NCT01521260 Implant Surface Decontamination in Peri-implantitis Treatment https://ClinicalTrials.gov/show/NCT01521260 Completed University Medical Center Groningen 2011-09-30
NCT01499225 A Clinical Trial of YH14642 in Patients With Chronic Periodontal Disease https://ClinicalTrials.gov/show/NCT01499225 Completed Yuhan Corporation 2013-07-31
NCT01427764 Dentin Hypersensitivity Following Non-surgical Periodontal Therapy With Hand or Ultrasonic Instruments https://ClinicalTrials.gov/show/NCT01427764 Completed Escola Bahiana de Medicina e Saude Publica 2010-01-31
NCT01422122 Study of Vitamin D Supplementation on Improvement of Gums Health https://ClinicalTrials.gov/show/NCT01422122 Completed Aga Khan University 2011-10-31
NCT04425343 Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing https://ClinicalTrials.gov/show/NCT04425343 Completed Ajman University 2018-09-15
NCT04422184 Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients https://ClinicalTrials.gov/show/NCT04422184 Recruiting University of Sao Paulo 2020-11-30
NCT04404374 Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD https://ClinicalTrials.gov/show/NCT04404374 Active, not recruiting Semmelweis University 2020-06-30
NCT04399187 Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement https://ClinicalTrials.gov/show/NCT04399187 Completed University of Messina 2019-09-01
NCT04399135 Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket https://ClinicalTrials.gov/show/NCT04399135 Active, not recruiting Qassim University 2021-02-25
NCT04390997 Determination of the Levels of Lipocalin-2 and Semaphorin3A https://ClinicalTrials.gov/show/NCT04390997 Recruiting Izmir Katip Celebi University 2020-09-30
NCT04381403 Development of a New Toothpaste for the Removal of Dental Calculus. https://ClinicalTrials.gov/show/NCT04381403 Active, not recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre 2019-03-10
NCT04356391 Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession https://ClinicalTrials.gov/show/NCT04356391 Active, not recruiting State University of New York at Buffalo 2020-06-30
NCT04345744 Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healing https://ClinicalTrials.gov/show/NCT04345744 Completed University of Pisa 2018-12-31
NCT04332965 Periostin and Non-Surgical Periodontal Treatment https://ClinicalTrials.gov/show/NCT04332965 Completed Kırıkkale University 2018-01-31
NCT04251858 Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes https://ClinicalTrials.gov/show/NCT04251858 Recruiting Universidade Metropolitana de Santos 2020-11-10
NCT04237662 Enamel Matrix Derivatives & Periodontal Therapy in Diabetic Patients https://ClinicalTrials.gov/show/NCT04237662 Recruiting University of Pisa 2023-01-01
NCT04223076 Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery https://ClinicalTrials.gov/show/NCT04223076 Recruiting University of Oslo 2019-12-20
NCT04209777 Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy https://ClinicalTrials.gov/show/NCT04209777 Completed Dow University of Health Sciences 2019-04-16
NCT04198610 Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study https://ClinicalTrials.gov/show/NCT04198610 Completed Krishnadevaraya College of Dental Sciences & Hospital 2017-08-28
NCT04180332 Anti Oxidant Enzymes and Total Antioxidant Levels in Diabetes Mellitus Type II Patients and Healthy Individuals With Periodontitis https://ClinicalTrials.gov/show/NCT04180332 Completed Ajman University 2018-08-10
NCT04173156 Treatment of Advanced Periodontitis Using an Oscillating Chitosan Device Versus Regular Curettes Alone https://ClinicalTrials.gov/show/NCT04173156 Recruiting Labrida AS 2020-01-15
NCT04169139 Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis https://ClinicalTrials.gov/show/NCT04169139 Active, not recruiting McGuire Institute 2020-05-15
NCT04149327 Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment https://ClinicalTrials.gov/show/NCT04149327 Completed University Medical Center Groningen 2019-12-31
NCT04145557 980nm Diode Laser in the Treatment of Periodontal Disease in Cardiac Patients https://ClinicalTrials.gov/show/NCT04145557 Recruiting Pomeranian Medical University Szczecin 2020-04-30
NCT04117451 The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health https://ClinicalTrials.gov/show/NCT04117451 Recruiting University of Plymouth 2020-07-01
NCT04082949 Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT04082949 Completed Inonu University 2018-12-10
NCT04059458 Mandibular Furcation III Regeneration (FURC-III-REGEN) https://ClinicalTrials.gov/show/NCT04059458 Recruiting University of Oslo 2027-06-15
NCT04059445 Mandibular Furcation II Regeneration https://ClinicalTrials.gov/show/NCT04059445 Recruiting University of Oslo 2027-06-15
NCT04051385 Assesment of Gingival Crevicular Fluid and Serum ErbB4/Neuregulin-4 Levels in Periodontal Disease and Health https://ClinicalTrials.gov/show/NCT04051385 Completed Abant Izzet Baysal University 2019-01-18
NCT04051255 Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis. https://ClinicalTrials.gov/show/NCT04051255 Active, not recruiting University of Campinas, Brazil 2020-03-01
NCT04036513 Minimally Invasive Non Surgical Therapy Versus Conventional Scaling and Root Planing for Treatment of Periodontitis https://ClinicalTrials.gov/show/NCT04036513 Recruiting University of Ljubljana 2021-04-02
NCT04023500 Supporting Oral Self-care of Patients With Periodontitis Through Motivational Interview https://ClinicalTrials.gov/show/NCT04023500 Active, not recruiting University of Turku 2015-11-01
NCT04017429 Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST) https://ClinicalTrials.gov/show/NCT04017429 Recruiting University of Oslo 2027-06-15
NCT04015427 Cement Excess at Single Implant Crowns Malmö/Lund https://ClinicalTrials.gov/show/NCT04015427 Recruiting University of Zurich 2019-12-31
NCT04006249 Haemochromatosis and Periodontitis https://ClinicalTrials.gov/show/NCT04006249 Completed Rennes University Hospital 2011-09-22
NCT03971981 Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect https://ClinicalTrials.gov/show/NCT03971981 Completed Università degli Studi di Sassari 2018-05-31
NCT03923465 Entire Papilla Preservation Technique With and Without Biomaterials in the Treatment of Isolated Intrabony Defects https://ClinicalTrials.gov/show/NCT03923465 Completed Dr. Aslan Private Perio Center 2018-09-16
NCT03919006 Netrin 1 and Its Receptor Unc5b as Markers of Periodontal Disease https://ClinicalTrials.gov/show/NCT03919006 Completed Abant Izzet Baysal University 2019-02-01
NCT03917030 Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects https://ClinicalTrials.gov/show/NCT03917030 Recruiting University of Oslo 2027-04-15
NCT03908606 Serum Hs-CRP in Periodontitis Patients With or Without Diabetes https://ClinicalTrials.gov/show/NCT03908606 Completed Cairo University 2019-01-02
NCT03839719 OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study. https://ClinicalTrials.gov/show/NCT03839719 Completed Government College of Dentistry, Indore 2019-04-26
NCT03816930 Evaluation of Gingival Health Parameters in Hybrid CAD / CAM Crowns Produced After Different Retraction Processes https://ClinicalTrials.gov/show/NCT03816930 Active, not recruiting Yuzuncu Yıl University 2020-01-17
NCT03814434 Surgical Treatment of Periimplantitis in Patients With Risk Factors https://ClinicalTrials.gov/show/NCT03814434 Recruiting University of Sao Paulo 2020-01-28
NCT03790904 Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash https://ClinicalTrials.gov/show/NCT03790904 Completed University of Baghdad 2019-03-31
NCT03765151 The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients https://ClinicalTrials.gov/show/NCT03765151 Recruiting The University of Hong Kong 2019-10-01
NCT03764410 Evaluation of Non - Surgical Periodontal Therapy in Diabetic Patients. https://ClinicalTrials.gov/show/NCT03764410 Completed Universidade Metropolitana de Santos 2017-10-15
NCT03753451 Influence of Periodontal Disease Treatment on Serum Levels of Sirtuin 1 and Mannose-binding Lectin https://ClinicalTrials.gov/show/NCT03753451 Completed InCor Heart Institute 2018-10-01
NCT03729167 Instrumentation Effectiveness of Modified, Area-Specific Hand Scalers During Non-Surgical Periodontal Therapy https://ClinicalTrials.gov/show/NCT03729167 Completed University of Michigan 2019-06-17
NCT03715374 Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects https://ClinicalTrials.gov/show/NCT03715374 Completed G. d’Annunzio University 2018-11-16
NCT03694496 The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong https://ClinicalTrials.gov/show/NCT03694496 Recruiting The University of Hong Kong 2020-07-28
NCT03671512 Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease https://ClinicalTrials.gov/show/NCT03671512 Completed Periovance, Inc 2020-01-17
NCT03641989 Correlation Between Oral Health and Systemic Inflammation (COHESION) https://ClinicalTrials.gov/show/NCT03641989 Completed Marshfield Clinic Research Foundation 2019-12-30
NCT03628872 Treatment of Periodontitis With Er:YAG Laser https://ClinicalTrials.gov/show/NCT03628872 Completed Columbia University 2019-05-01
NCT03622255 Evaluation of Enamel Matrix Derivative as an Adjunct to Minimally Invasive Non-surgical Treatment of Intrabony Defects. https://ClinicalTrials.gov/show/NCT03622255 Recruiting Aristotle University Of Thessaloniki 2019-12-30
NCT03550651 Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mouthrinse https://ClinicalTrials.gov/show/NCT03550651 Completed Government College of Dentistry, Indore 2017-05-15
NCT03544931 Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy https://ClinicalTrials.gov/show/NCT03544931 Completed University of Pisa 2018-01-01
NCT03540498 Study of Colonization of Strains L.Plantarum and L.Brevis in the Product AB-DENTALAC Chewing Gum https://ClinicalTrials.gov/show/NCT03540498 Completed AB Biotics, SA 2016-11-24
NCT03525457 Response to Periodontal Therapy in a Chronic Kidney Disease Population https://ClinicalTrials.gov/show/NCT03525457 Recruiting Pontificia Universidad Catolica de Chile 2019-08-31
NCT03501316 The Immune Response After Periodontal Treatment https://ClinicalTrials.gov/show/NCT03501316 Completed University of Glasgow 2019-08-01
NCT03474146 Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract https://ClinicalTrials.gov/show/NCT03474146 Completed Government College of Dentistry, Indore 2017-07-22
NCT03452891 Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients https://ClinicalTrials.gov/show/NCT03452891 Recruiting University of Nebraska 2020-07-01
NCT03444363 Periodontal Treatment With Diode Laser in the Patients With Diabetes Melitus https://ClinicalTrials.gov/show/NCT03444363 Completed Çanakkale Onsekiz Mart University 2014-02-15
NCT03442920 Evaluation of Periodontal Diseases and Obesity in Women https://ClinicalTrials.gov/show/NCT03442920 Completed Kocaeli University 2015-06-11
NCT01215201 Diode Laser Study for Periodontal Maintenance Patients https://ClinicalTrials.gov/show/NCT01215201 Completed University of Nebraska 2011-06-30
NCT01201746 Influence of Periodontal Treatment on Systemic Inflammatory Mediators https://ClinicalTrials.gov/show/NCT01201746 Completed Sheikh Zayed Federal Postgraduate Medical Institute 2009-04-30
NCT01198509 Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA) https://ClinicalTrials.gov/show/NCT01198509 Completed NYU Langone Health 2013-01-31
NCT01128374 The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT01128374 Completed The University of Texas Health Science Center, Houston 2012-09-30
NCT01118143 Oral Health Literacy Tailored Communication https://ClinicalTrials.gov/show/NCT01118143 Completed University of Tromso 2012-02-29
NCT01113528 Omega-3 and Aspirin in Periodontal Regeneration https://ClinicalTrials.gov/show/NCT01113528 Completed October 6 University 2009-12-31
NCT01046435 Effects of Periodontal Therapy on Systemic Inflammation https://ClinicalTrials.gov/show/NCT01046435 Completed University of Chile 2009-03-31
NCT00955643 Periodontal Treatment Associated With Hyperbaric Oxygen Therapy https://ClinicalTrials.gov/show/NCT00955643 Completed Escola Bahiana de Medicina e Saude Publica NA
NCT00937976 Treatment for Periodontal Disease in Dialysis Patients https://ClinicalTrials.gov/show/NCT00937976 Completed University of North Carolina, Chapel Hill 2010-06-30
NCT00893802 Influence of Periodontal Treatment During Pregnancy in Adverse Pregnant Outcomes https://ClinicalTrials.gov/show/NCT00893802 Completed University of Sao Paulo 2002-08-31
NCT03244943 Cytokine Profiles in Breast Cancer Patients Undergoing Chemotherapy https://ClinicalTrials.gov/show/NCT03244943 Completed University of Sao Paulo 2016-12-12
NCT03620396 Comparison of Serum Trefoil Factor 3 in Patients With Gingivitis and Periodontitis After Scaling and Root Planing https://ClinicalTrials.gov/show/NCT03620396 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2017-01-17
NCT04330469 Periodontal Therapy and Oral-gut-hepatic Axis Cirrhosis: a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT04330469 Recruiting Postgraduate Institute of Medical Education and Research 2021-03-30
NCT03590093 Amelogenins and Systemic Inflammation After Periodontal Surgical Therapy https://ClinicalTrials.gov/show/NCT03590093 Completed University of Pisa 2017-12-01
NCT02906982 Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis https://ClinicalTrials.gov/show/NCT02906982 Completed Glo Science, Inc. 2015-12-31
NCT03997552 NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration https://ClinicalTrials.gov/show/NCT03997552 Recruiting Universidad de Murcia 2020-09-30
NCT03939936 The Effect of Periodontal Treatment on Psoriasis https://ClinicalTrials.gov/show/NCT03939936 Completed Tokat Gaziosmanpasa University 2018-01-30
NCT00763256 The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics https://ClinicalTrials.gov/show/NCT00763256 Completed Colgate Palmolive 2009-08-31
NCT00757159 Study on Regenerative Treatment of Intra-bony Defects https://ClinicalTrials.gov/show/NCT00757159 Completed Technische Universität Dresden 2012-01-31
NCT00702429 Immunoregulation of Periodontal Disease https://ClinicalTrials.gov/show/NCT00702429 Completed Assistance Publique Hopitaux De Marseille 2010-07-31
NCT02066337 Effect of Ozone Gel on Treatment of Chronic Periodontitis https://ClinicalTrials.gov/show/NCT02066337 Completed October 6 University 2014-01-31
NCT00379548 Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study https://ClinicalTrials.gov/show/NCT00379548 Completed Joslin Diabetes Center 2008-07-31
NCT00255970 Regenafil Versus Demineralized Freeze Dried Bone Allograft (DFDBA) for Periodontal Defects https://ClinicalTrials.gov/show/NCT00255970 Completed RTI Surgical 2007-11-30
NCT02845024 The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02845024 Completed Islamic Azad University, Tehran 2015-12-31
NCT00196456 Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo) https://ClinicalTrials.gov/show/NCT00196456 Completed University Medicine Greifswald NA
NCT00167466 Placebo Controlled Trial of a Titanium Dioxide Semiconductor Toothbrush on Mild-to-moderate Gum Disease https://ClinicalTrials.gov/show/NCT00167466 Completed University of Saskatchewan 2010-05-31
NCT00127244 Study Comparing Two Different Methods of Treating Periodontal Disease https://ClinicalTrials.gov/show/NCT00127244 Completed The Forsyth Institute NA
NCT00093236 Impact of Gum Infection on Heart Disease https://ClinicalTrials.gov/show/NCT00093236 Completed Boston University 2011-04-30
NCT00066066 Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers https://ClinicalTrials.gov/show/NCT00066066 Completed The Forsyth Institute 2009-07-31
NCT00066001 Microbial Associations in Periodontal Health and Disease https://ClinicalTrials.gov/show/NCT00066001 Completed The Forsyth Institute 2007-12-31
NCT00001698 Randomized, Double Blind, Placebo-Controlled, Phase IIB Trial of Ketorolac Mouth Rinse Evaluating the Effect of Cyclooxygenase Inhibition on Oropharyngeal Leukoplakia: Collaborative Study of the NCI, NIDCD and the NIDCR https://ClinicalTrials.gov/show/NCT00001698 Completed National Institutes of Health Clinical Center (CC) NA
NCT00016835 Treating Periodontal Infection: Effects on Glycemic https://ClinicalTrials.gov/show/NCT00016835 Completed University of Michigan 2004-09-03
NCT00004640 “Clinical Trials to Enhance Elders’ Oral Health” (“TEETH”) https://ClinicalTrials.gov/show/NCT00004640 Completed University of Washington 2008-05-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03395041 Periodontal Disease, Inflammation and Acute Coronary Syndromes https://ClinicalTrials.gov/show/NCT03395041 Recruiting Cardio Med Medical Center 2021-01-15
NCT03391349 Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects https://ClinicalTrials.gov/show/NCT03391349 Completed Meenakshi Ammal Dental College and Hospital 2017-07-22
NCT03371446 DNA Methylation Profile of the SOCS-1 Gene Promoter in Smokers Patients With Chronic Periodontitis. https://ClinicalTrials.gov/show/NCT03371446 Completed University of Sao Paulo 2017-10-16
NCT03787875 Impact of Periodontal Treatment on the RANKL/OPG Ratio in Crevicular Fluid https://ClinicalTrials.gov/show/NCT03787875 Completed University of Valencia 2016-06-05
NCT03345329 Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms https://ClinicalTrials.gov/show/NCT03345329 Completed General Biologicals Corporation 2016-03-30
NCT03265821 Influence of Smoking on Periodontal Healing One Year After Active Treatment https://ClinicalTrials.gov/show/NCT03265821 Completed Dalarna County Council, Sweden 2015-12-31
NCT03225950 Interaction Between Immune Cells and Bacteria Associated With Periodontitis https://ClinicalTrials.gov/show/NCT03225950 Completed University of Copenhagen 2018-10-12
NCT03161301 Role of IL-37 Genetic Variants in Modulating Innate Immune Response to Periodontal Pathogens https://ClinicalTrials.gov/show/NCT03161301 Completed University of North Carolina, Chapel Hill 2019-05-24
NCT03064178 Use of Pain Medication Following Periodontal Procedures https://ClinicalTrials.gov/show/NCT03064178 Completed Brock University 2016-03-07
NCT02935868 Periodontal and Salivary Evaluation of Type 1 Diabetes Mellitus Patients https://ClinicalTrials.gov/show/NCT02935868 Completed University of Sao Paulo 2016-09-30
NCT02903264 Gestational Diabetes Mellitus, Obesity and Periodontal Disease https://ClinicalTrials.gov/show/NCT02903264 Completed University of Sao Paulo 2016-09-30
NCT02894463 Study Aimed at Detecting Potential Abuse of Nitrous Oxide in Children During Dental Care https://ClinicalTrials.gov/show/NCT02894463 Completed Nantes University Hospital 2015-05-31
NCT02848378 Advanced Oxidation Protein Product and Monocyte Chemoattractant Protein-1 in Periodontal Disease https://ClinicalTrials.gov/show/NCT02848378 Completed Kırıkkale University 2015-01-31
NCT02826720 Is There a Relationship Between Hyperlipidemia and Periodontitis? https://ClinicalTrials.gov/show/NCT02826720 Completed Marmara University 2016-01-31
NCT02808130 PERIODONTAL DISEASE AND HYPERLIPIDEMIA https://ClinicalTrials.gov/show/NCT02808130 Completed Ondokuz Mayıs University 2014-08-31
NCT02794012 Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT02794012 Completed University of Colorado, Denver 2017-12-31
NCT02789306 Preventive Maintenance Therapy on Peri-implant Diseases https://ClinicalTrials.gov/show/NCT02789306 Completed Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain 2017-01-01
NCT02750956 Endocan, VEGF and TNF-alpha Levels in Periodontal Disease and After Treatment https://ClinicalTrials.gov/show/NCT02750956 Completed Bulent Ecevit University 2015-12-31
NCT02615626 Visfatin Levels Before and After Periodontal Treatment https://ClinicalTrials.gov/show/NCT02615626 Completed Bulent Ecevit University 2013-10-31
NCT01712672 Bacterial Arrangement on the Teeth https://ClinicalTrials.gov/show/NCT01712672 Completed National Institutes of Health Clinical Center (CC) 2016-01-07
NCT02433405 Serum Amyloid A Protein And Fetuin A Levels https://ClinicalTrials.gov/show/NCT02433405 Completed Bulent Ecevit University 2014-04-30
NCT02394860 Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension https://ClinicalTrials.gov/show/NCT02394860 Recruiting University Hospital, Strasbourg, France 2020-05-31
NCT02289066 Impact of Periodontal Disease on Outcomes in Diabetes https://ClinicalTrials.gov/show/NCT02289066 Completed University of Nevada, Reno 2015-06-30
NCT02184962 Periodontal Disease and Post-menopausal Osteoporosis https://ClinicalTrials.gov/show/NCT02184962 Completed Universidad Nacional de Córdoba 2013-09-30
NCT02177591 Observational Study of the Association Between Periodontal Disease and Cardiovascular Disease https://ClinicalTrials.gov/show/NCT02177591 Completed Texas Tech University Health Sciences Center 2015-05-31
NCT02127203 Nitro-oxidative Stress in Periodontitis https://ClinicalTrials.gov/show/NCT02127203 Completed Damascus University 2015-09-30
NCT04450810 Role of ET-1 in Periodontitis and Diabetes https://ClinicalTrials.gov/show/NCT04450810 Completed University of Messina 2019-12-28
NCT01881074 Periodontal Treatment Response in Type II Diabetic Patients https://ClinicalTrials.gov/show/NCT01881074 Completed University of Florida 2015-12-31
NCT01785355 The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients https://ClinicalTrials.gov/show/NCT01785355 Recruiting Anemia Working Group Romania 2021-09-30
NCT01584479 Periodontal Disease Prevention Study https://ClinicalTrials.gov/show/NCT01584479 Completed University of Michigan 2012-03-31
NCT01568697 Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis) https://ClinicalTrials.gov/show/NCT01568697 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT01489839 Biomarkers of Periodontal Disease Progression https://ClinicalTrials.gov/show/NCT01489839 Completed The Forsyth Institute 2016-06-30
NCT01399034 Epigenetics, DNA Methylation Patterns and Periodontal Disease https://ClinicalTrials.gov/show/NCT01399034 Completed University of North Carolina, Chapel Hill 2011-02-28
NCT01376791 Assess the Effect of Treating Periodontal Disease on Cardiovascular Function in Young Adults https://ClinicalTrials.gov/show/NCT01376791 Completed San Diego State University 2012-12-31
NCT04417322 Serum A.Actinomycetemcomitans Antibodies and Periodontitis https://ClinicalTrials.gov/show/NCT04417322 Completed University of Messina 2020-03-02
NCT04407026 Oral and Systemic Levels of TFF-1 and TTF-3 in Periodontal Diseases https://ClinicalTrials.gov/show/NCT04407026 Completed Aydin Adnan Menderes University 2018-03-01
NCT04382105 Serum P.Gingivalis Antibodies and Periodontitis https://ClinicalTrials.gov/show/NCT04382105 Completed University of Messina 2020-02-15
NCT04381273 Oral Health and Psychosocial Factors During the Covid-19 Pandemic https://ClinicalTrials.gov/show/NCT04381273 Recruiting Heidelberg University 2020-07-31
NCT04380922 Prevalence of Periodontal Diseases in IBD https://ClinicalTrials.gov/show/NCT04380922 Recruiting CHU de Reims 2021-07-19
NCT04335344 Role of suPAR in Periodontitis and CVD https://ClinicalTrials.gov/show/NCT04335344 Completed University of Messina 2018-09-21
NCT04274855 Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior https://ClinicalTrials.gov/show/NCT04274855 Recruiting Ain Shams University 2020-11-30
NCT04271787 New Periodontal Classification https://ClinicalTrials.gov/show/NCT04271787 Completed Beni-Suef University 2019-06-30
NCT04268381 Oral and Systemic aMMP-8 in Periodontal Disease https://ClinicalTrials.gov/show/NCT04268381 Recruiting Aydin Adnan Menderes University 2020-03-20
NCT04253613 Laser Biostimulation in Periodontal Treatment https://ClinicalTrials.gov/show/NCT04253613 Completed Ondokuz Mayıs University 2014-06-15
NCT04209231 Effect of Vitamin D on Periodontal Disease https://ClinicalTrials.gov/show/NCT04209231 Completed Recep Tayyip Erdogan University Training and Research Hospital 2016-04-30
NCT04143568 Circulating Progenitor Cells Levels in Periodontal Disease Patients https://ClinicalTrials.gov/show/NCT04143568 Completed University of Messina 2018-10-30
NCT04135222 Evaluation of Periodontal Phenotype Using CBCT, Computed Aided Design (CAD) and Prosthetic-driven Implant Planing (PDIP). https://ClinicalTrials.gov/show/NCT04135222 Completed Wroclaw Medical University 2019-05-13
NCT04127487 Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects https://ClinicalTrials.gov/show/NCT04127487 Recruiting Meenakshi Ammal Dental College and Hospital 2020-11-01
NCT04127474 Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease https://ClinicalTrials.gov/show/NCT04127474 Recruiting Meenakshi Ammal Dental College and Hospital 2019-12-20
NCT04081025 Oral Health and Risk Factors for Oral Disease https://ClinicalTrials.gov/show/NCT04081025 Active, not recruiting Dalarna County Council, Sweden 2020-12-30
NCT04045808 Relationship of Oral Status to Coronary Artery Disease https://ClinicalTrials.gov/show/NCT04045808 Completed Baskent University 2011-01-01
NCT04024644 Third Molar: Caries, Periodontal Disease and Quality of Life https://ClinicalTrials.gov/show/NCT04024644 Completed University of Sao Paulo 2013-10-01
NCT04017078 Assessment of Carotid Artery Calcifications https://ClinicalTrials.gov/show/NCT04017078 Completed Baskent University 2018-09-25
NCT04012983 Possible Role of Gingival Crevicular Fluid Levels of Chemerin and Fibroblast Growth Factor 21 as Biomarkers of Periodontal Disease in Diabetic and Non-diabetic Patients https://ClinicalTrials.gov/show/NCT04012983 Completed Cairo University 2018-08-01
NCT03934957 Hamburg City Health Study - a German Cohort Study https://ClinicalTrials.gov/show/NCT03934957 Recruiting Universitätsklinikum Hamburg-Eppendorf 2022-12-31
NCT03910205 Tumor Necrosis Factor-alpha and Interleukin-18 Levels in Children With Gingivitis and Type 1 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT03910205 Completed Aydin Adnan Menderes University 2019-06-30
NCT03809676 Periodontal Status and Dental Behavior of Heart Trasplant Recipients and Healthy Controls https://ClinicalTrials.gov/show/NCT03809676 Completed Baskent University 2019-01-10
NCT03775967 Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients https://ClinicalTrials.gov/show/NCT03775967 Completed Ajman University 2019-01-10
NCT03727035 Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects https://ClinicalTrials.gov/show/NCT03727035 Recruiting Meenakshi Ammal Dental College and Hospital 2019-11-30
NCT03721159 Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects https://ClinicalTrials.gov/show/NCT03721159 Completed Meenakshi Ammal Dental College and Hospital 2018-09-01
NCT03703648 Post-radiation Dental Disease Amongst Head and Neck Cancer Patients https://ClinicalTrials.gov/show/NCT03703648 Recruiting Belfast Health and Social Care Trust 2023-05-31
NCT03660410 Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil https://ClinicalTrials.gov/show/NCT03660410 Completed Universidade Metropolitana de Santos 2017-05-02
NCT03649789 Periodontal Outcomes After Sanative Therapy https://ClinicalTrials.gov/show/NCT03649789 Completed Brock University 2019-03-30
NCT03648723 The Effect of Periodontal Disease Treatment in Patients With Kidney Disease https://ClinicalTrials.gov/show/NCT03648723 Completed TC Erciyes University 2017-01-10
NCT03610841 Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor https://ClinicalTrials.gov/show/NCT03610841 Recruiting Recep Tayyip Erdogan University Training and Research Hospital 2018-09-17
NCT03594968 Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions https://ClinicalTrials.gov/show/NCT03594968 Recruiting Recep Tayyip Erdogan University Training and Research Hospital 2019-03-30
NCT03558906 TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases https://ClinicalTrials.gov/show/NCT03558906 Completed Aydin Adnan Menderes University 2016-03-02
NCT03470987 The Role of Visfatin in Obesity and Periodontal Disease https://ClinicalTrials.gov/show/NCT03470987 Completed Gazi University 2014-09-30
NCT03437798 Genomic Determinants and Shared Genetic Pathways of Periodontal Disease https://ClinicalTrials.gov/show/NCT03437798 Recruiting Tufts University 2022-05-31
NCT01234948 Oral Malodour and Periodontal Disease-related Parameters https://ClinicalTrials.gov/show/NCT01234948 Completed Aristotle University Of Thessaloniki 2009-01-31
NCT01180920 The Importance of Periostin in Periodontal Health and Disease https://ClinicalTrials.gov/show/NCT01180920 Completed University of Michigan 2013-02-28
NCT01156155 Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT01156155 Completed University of Nebraska 2012-07-31
NCT01154855 Periodontal Disease and Circulatory Microbial Components https://ClinicalTrials.gov/show/NCT01154855 Completed University of Michigan 2015-05-31
NCT01130207 Microbes and Bariatric Surgery https://ClinicalTrials.gov/show/NCT01130207 Completed State University of New York - Upstate Medical University 2013-08-31
NCT00855504 Association of Periodontitis and Preeclampsia During Pregnancy https://ClinicalTrials.gov/show/NCT00855504 Completed Maulana Azad Medical College 2011-09-30
NCT01693731 Oral Health in Breast Cancer Survivors on Aromatase Inhibitors https://ClinicalTrials.gov/show/NCT01693731 Completed University of Michigan 2015-03-31
NCT03603236 Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease https://ClinicalTrials.gov/show/NCT03603236 Recruiting Recep Tayyip Erdogan University Training and Research Hospital 2018-09-17
NCT03507868 YKL-40 and IL-6 Levels in Periodontal Disease https://ClinicalTrials.gov/show/NCT03507868 Completed Aydin Adnan Menderes University 2017-04-30
NCT03132207 The 4th Month Oral Consultation at Pregnant Women https://ClinicalTrials.gov/show/NCT03132207 Completed Nantes University Hospital 2018-03-16
NCT02941887 Global Behavior and Periodontal Disease in Down’s Syndrome Patients https://ClinicalTrials.gov/show/NCT02941887 Completed University of Sao Paulo 2016-10-31
NCT00569075 Apoptic Biomarkers of Periodontal Disease https://ClinicalTrials.gov/show/NCT00569075 Completed University of Michigan 2009-10-31
NCT00490165 Periodontal and Periapical Inflammation and Pregnancy https://ClinicalTrials.gov/show/NCT00490165 Completed University of Mississippi Medical Center 2011-12-31
NCT00001726 Study of the Composition of Dental Plaque https://ClinicalTrials.gov/show/NCT00001726 Completed National Institutes of Health Clinical Center (CC) 2009-08-03

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03407911 Microbiota Around Periodontal Teeth and Implants Affected by Peri-implant Disease. https://ClinicalTrials.gov/show/NCT03407911 Completed Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele 2018-04-01
NCT03088228 Maternal Periodontal Status and Cytokines in Preeclampsia https://ClinicalTrials.gov/show/NCT03088228 Completed Yuzuncu Yıl University 2016-08-15
NCT01900535 Evaluation and Comparison of the Efficacy of Triphala Mouthwash and 0.2% Chlorhexidine https://ClinicalTrials.gov/show/NCT01900535 Completed Tatyasaheb Kore Dental College 2013-02-28
NCT01866761 Relationship Analysis Between Periodontal Disease and Atherosclerosis in Japanese Medical Cooperation Services https://ClinicalTrials.gov/show/NCT01866761 Completed Okayama University 2012-01-31
NCT03805724 Entamoeba Gingivalis and Periodontal Disease https://ClinicalTrials.gov/show/NCT03805724 Completed Cairo University 2019-01-18
NCT03789565 Hepcidin Levels in Periodontal Health and Disease https://ClinicalTrials.gov/show/NCT03789565 Completed Bulent Ecevit University 2018-01-20
NCT03663140 Neurogenic Inflammation in Peri-implant and Periodontal Diseases https://ClinicalTrials.gov/show/NCT03663140 Completed Ondokuz Mayıs University 2013-09-15
NCT03549247 Oral Health Related Quality of Life and Periodontal Diseases https://ClinicalTrials.gov/show/NCT03549247 Completed Ondokuz Mayıs University 2017-07-30
NCT03527901 Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease https://ClinicalTrials.gov/show/NCT03527901 Completed Aydin Adnan Menderes University 2016-03-01
NCT03788473 "Periodontal Disease as a Possible Risk Factor for Complications During Pregnancy and Childbirth https://ClinicalTrials.gov/show/NCT03788473 Recruiting Universidad de Granada 2019-07-26